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TB5

TB-500

Synthetic Thymosin Beta-4 fragment

RepairRegenerationFlexibility

A synthetic fragment of Thymosin Beta-4 that promotes cell migration, flexibility, and tissue regeneration.

01Overview

TB-500 corresponds to the biologically active region of Thymosin Beta-4, a naturally occurring actin-regulating protein present in most tissues and in high concentration at wound sites.

It is studied for its systemic, whole-body distribution and role in recovery and flexibility.

02Mechanism

  • Binds and sequesters G-actin, regulating the actin cytoskeleton that governs cell movement.
  • Promotes migration of endothelial and repair cells to injured tissue.
  • Supports angiogenesis and reduces inflammatory signaling in models.

03Research uses

  • Soft-tissue and tendon-repair research
  • Cardiac and muscle-regeneration models
  • Flexibility and range-of-motion studies

04Key findings

  • Preclinical models show improved wound closure and endothelial migration.
  • Often studied alongside BPC-157 for complementary repair mechanisms.
  • Distributes systemically rather than acting only at a local site.

05Handling & reconstitution

  • Supplied lyophilized as a white powder.
  • Reconstitute with bacteriostatic water; swirl gently.
  • Store lyophilized frozen; keep reconstituted solution refrigerated and protected from light.
Research use only

All information on peptek is aggregated from public sources for research and educational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease. Peptide products referenced here are not for human consumption of any kind. Always consult a qualified healthcare professional before beginning any research protocol.