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EPI

Epitalon

Telomerase-modulating tetrapeptide

Anti-agingLongevitySleep

A synthetic tetrapeptide (AEDG) studied for pineal regulation, circadian rhythm, and telomere biology.

01Overview

Epitalon (also spelled Epithalon) is a four-amino-acid peptide derived from epithalamin, a pineal-gland extract characterized by Russian researcher Vladimir Khavinson.

It is investigated primarily in the context of aging, circadian regulation, and telomere maintenance.

02Mechanism

  • Reported to influence telomerase activity, the enzyme that maintains chromosomal telomeres.
  • Modulates pineal function and endogenous melatonin rhythm.
  • Acts as a short-signal peptide with regulatory rather than structural roles.

03Research uses

  • Longevity and cellular-senescence research
  • Circadian-rhythm and melatonin studies
  • Antioxidant-defense models

04Key findings

  • Cell-culture studies report increased telomerase activity and extended replicative capacity of fibroblasts.
  • Animal work has explored effects on lifespan markers and melatonin secretion.
  • Human data remain limited and largely from a single research lineage.

05Handling & reconstitution

  • Supplied lyophilized; highly water-soluble on reconstitution.
  • Reconstitute with bacteriostatic water; swirl gently.
  • Store frozen when lyophilized; short reconstituted shelf life — keep cold and dark.
Research use only

All information on peptek is aggregated from public sources for research and educational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease. Peptide products referenced here are not for human consumption of any kind. Always consult a qualified healthcare professional before beginning any research protocol.